With obesity rates rising to epidemic levels across the country, many doctors are searching for creative treatments for their overweight patients. Many have begun combining medications, using off-label prescription drugs that are intended for other uses, in combination with other off-label prescription drugs that work through similar mechanisms. One example is a weight loss drug combo using a newly approved medication, Belviq (Lorcaserin), with phentermine, an older diet drug. While creating drug combos is an age-old practice, there are many potential hazards. Phentermine, a powerful stimulant and appetite suppressant, was removed from the market due to its dangerous side effects. Belviq, twice denied for FDA approval, is considered a controlled substance with hallucinogenic effects. Although the side effects of each of these two drugs used independently is clear, using them in combination for weight loss has not been studied to date.