Print | Try ellagic acid in muscadines and feel the benefits
The study aimed to determine the antioxidant effect of ellagic acid on the heart and liver and see if it could reduce the toxicity induced by cisplatin.
Cisplatin is one of the most active cytotoxic agents in the treatment of cancer. High doses of cisplatin have also been known to produce hepatotoxicity, and several studies suggest that antioxidants in supplements can reduce cisplatin-induced hepatotoxicity.
For the experiment, 24 rats were divided into four groups which were given either saline, ellagic acid, cisplatin or ellagic acid and cisplatin for a period of ten days. At the end of the study period the rats liver and heart levels were analyzed. It was found that damage induced by cisplatin was reduced by the introduction of ellagic acid.
The authors commented: “In conclusion, we have shown that experimental cisplatin administration increased lipid peroxidation in rats. Ellagic acid protects against cisplatin-induced toxicity by inhibition of the inactivation of glutathione and antioxidant system by cisplatin, up-regulation of GSH-Px and CAT levels in the liver and heart. Thus, the moderate ellagic acid supplementation may play a protective role against cisplatin-induced oxidative stress.”
Mary Green, spokesperson for Muscadine grape supplier, Muscadinex, commented: “Its exciting to see such positive developments into treating diseases that effect so many. With the role ellagic acid played in this study it re-confirms our commitment to Muscadinex, our supplement containing ellagic acid, resveratrol and quercetin.”
Muscadinex is made from 100% pure muscadine grape extract and because the muscadine grape seed is the only form of grape to contain quercetin, reveratrol and ellagic acid, you are getting a super dose of antioxidants that work in synergy to stave off the diseases associated with old age.
Mary Green continued: “We are committed to producing the finest health supplements using only the best ingredients, and with Muscadinex you are simply getting that…the best!
To read more about muscadine grapes and their benefits visit Muscadinex
Other press releases from Muscadinex
- Ellagic Acid From Muscadine Grapes Can Combat Oxidative Stress in Diabetic Rats - September 29th, 2011
- Resveratrol and Quercetin Can Help With Obesity and Osteoperosis - September 23rd, 2011
- Resveratrol Can Combat Metabolic Syndrome - September 8th, 2011
- Resveratrol and ellagic acid are successful at combating skin cancer when combined - September 2nd, 2011
- Could Resveratrol Help Combat Breast Cancer - August 23rd, 2011
