Epione Medical Corporation

Botox: Can the Miracle Wrinkle-Busting Drug Also Cure Depression?

Entrepreneur Magazine reported that a newly published study indicates that Botox injections might offer an effective treatment for severe depression. Simon Ourian, M.D., of Epione Beverly Hills, says that he’s encouraged by the results of the study and hopes that additional work will be done to help those that suffer from this debilitating condition.


Beverly Hills, CA -- (ReleaseWire) -- 04/03/2014 -- As reported online March 24, 2014 by Entrepreneur Magazine, in a report titled “Botox as a Treatment for Depression? It’s Not as Crazy as it Sounds,” a study recently published in the Journal of Psychiatric Research indicates that Botox injections may be helpful for treating major depression (see: goo.gl/uv1oLj). The study involved 74 patients with severe depression who were assigned to one of two groups. Members of one group were given placebo saline injections and members of the other group were given Botox injections. The results of the study showed that 52 percent of the patients who received Botox reported relief from their depression. Only 15 percent of the placebo group reported any benefit.

“This is very exciting news,” says Dr. Ourian, Medical Director of Epione Beverly Hills. “As noted in the article, there have been previous studies that investigated the impact of Botox on mood and depression, including the 2008 University of Cardiff study.”

There are several reasons that the authors of the new study believe Botox is effective for treating depression. Frowning affects the way a person feels about him or herself. It also affects the way other people respond to him or her. If a person's ability to frown is inhibited, then they can interact more positively with the people around them. The researchers also believe that frowning itself may contribute to depression. Tensing up the muscles to frown will cause the brain to create the same emotional experience.

The idea that a facial expression can create or enhance an emotional response is not new. This idea dates back to 1872 when the facial feedback hypothesis was proposed by Charles Darwin. Darwin wrote that an emotion is intensified when it is freely expressed on the outside.

The authors of the study predict that Botox treatments may help lower distress signals and positively influence mood. Regardless of whether or not one believes that Botox can actually be an effective treatment for depression, the results of the study show how important one’s facial expressions can be. “If we choose to show our depressed mood and frown instead of smiling during unpleasant circumstances,” says Dr. Ourian, “then our ability to have a more positive outlook will be negatively impacted.”

About Epione Beverly Hills
Epione Beverly Hills has been a leader in minimally-invasive aesthetic medicine and laser technology. Products offered include Botox, Radiesse, Sculptra, Restylane, and Juvéderm. Procedures are available to treat or reverse conditions such as wrinkles, stretch marks, varicose veins, cellulite, skin discoloration, acne, and acne associated scars. More information about treating Botox can be found on Epione’s website.