Hialeah Gardens, FL -- (ReleaseWire) -- 07/16/2014 -- Levetiracetam manages epilepsy in cats and dogs that are not responsive to other treatments. Unlike most drugs, it is not metabolized by the system in the liver by enzymes known as Cytochrome P450s, making it a good choice for animals with liver disease. It is not known to interact with any other drugs. Cats and dog on phenobarbital or potassium bromide that does not respond well to treatment, which can be as high as 70 percent, are given levetiracetam in addition to their current medication. Animals that have seizures because of hepatic encephalopathy, which results when the liver is not cleaning out the blood which lets toxins get to the brain, benefits from this drug.
Unfortunately, a tolerance to the drug may develop and seizures may be observed when they become tolerant. Drowsiness, some gastrointestinal upset such as vomiting and diarrhea and behavioral changes are the only known side effects. Cats may have less of an appetite on levetiracetam.Insulin Animals with kidney disease should be closely monitored if given the drug because that is how it leaves the body and it should be tapered when discontinuing treatment to prevent seizures that could occur during withdrawal.
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