The U.S. market for soft tissue reinforcement and regeneration includes medical graft devices that are designed to reinforce and regenerate soft tissues. Soft tissues are defined as aggregations of similarly specialized cells which collectively function to connect, support or surround other structures and organs of the body. These tissues include tendons, ligaments, fascia, skin, fibrous tissues, fat, synovial membranes, muscles, nerves and blood vessels. Collagen, the most abundant protein in mammals, is one of the characteristic elements inside the extracellular matrix of soft tissue and, as such, plays a critical role in soft tissue repair. Since soft tissue essentially makes up the majority of a person and there are countless medical conditions associated with soft tissue problems, a select group of large markets related to soft tissue repair will be covered in this report, including breast reconstruction, hernia repair, dural repair, vaginal slings, skin repair, sports medicine and tendon reinforcement, and dental soft tissue regeneration.