New York, NY -- (ReleaseWire) -- 04/22/2013 -- Astex Pharmaceuticals, Inc. (NASDAQ:ASTX) announced that SGI-110 was featured in an oral presentation on Tuesday, April 9 at the American Association of Cancer Research (AACR) in Washington, DC.
Researchers from Indiana University presented data from preclinical models supporting the ovarian cancer epigenetic chemosensitization effect of SGI-110. In established ovarian cancer xenograft models, SGI-110 in combination with platinum significantly delayed tumor growth compared to platinum alone.
The researchers also showed that SGI-110 induced demethylation and increased expression of several tumor suppressor and tumor differentiation genes. In addition, SGI-110 slowed the repair of platinum DNA damage.
SGI-110 is a novel small molecule, DNA-hypomethylating agent administered as a single low volume subcutaneous injection.
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Groupon Inc. (NASDAQ:GRPN) traded at $ 6.36 in the last session, which is +0.24 (3.92%). The stock has a Range of 6.16 - 6.39. The stock has a 52 week low and high of 2.60 - 14.93 respectively. The stock has a Market Cap of 4.19B. The stock traded a volume of 8.79M. The stock has a 30 day average volume of 13.74M.
Groupon, Inc. offers online retail services. The Company provides daily deal on the stuff to do, eat, see and buy in more than 500 markets in 44 countries. It has offices across North America, Europe, Latin America, Asia and other parts of the world. The Company provides an online service that lets groups of people create campaigns to pool resources, including money and personal commitments to take action. It allows users to sell products and transact business online.
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