Each year, millions of people are affected by respiratory diseases across the world, due to which, the use of inhalable biologics is also increasing. Inhalable biologics are agents that are formed from the products of living (plant or microorganisms) sources, which are used for treating chronic diseases and acute diseases such as asthma, COPD, and cystic fibrosis, among others. Inhalable biologics are beneficial over the conventional systems because of their target specific working. Inhaled and nasal delivery of biologic products are a more convenient method of administrating compounds systematically. Inhalable biologics used for long-term diseases give opportunity for the repurposing of existing products for inhaled and nasal delivery to boost patient experience, and help decrease complications. Inhalable biologics is the way of getting biological drugs specifically to the target by inhaling the drug. These inhalable biologics are sometimes synthesized through recombinant DNA technology, due to which, they work efficiently in the body and have various kinds of benefits accordingly.